Kunitz_BPTI: Kunitz/Bovine pancreatic trypsin inhibitor domain
| PAG Title | Kunitz_BPTI: Kunitz/Bovine pancreatic trypsin inhibitor domain |
| PAG ID | PEX002191 |
| Type | A |
| Source Link |  Pfam |
| Publication Reference | NA |
| PAG Description | Indicative of a protease inhibitor, usually a serine protease inhibitor. Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure. Certain family members are similar to the tick anticoagulant peptide (TAP, Swiss:P17726). This is a highly selective inhibitor of factor Xa in the blood coagulation pathways 1. TAP molecules are highly dipolar 2, and are arranged to form a twisted two- stranded antiparallel beta-sheet followed by an alpha helix 1. |
| Species | Homo sapiens |
| nCoCo Score | 0 |
| Base PAG ID | PEX002191 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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